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Neoadjuvant chemotherapy
Neoadjuvant chemotherapy is a course ofcancertreatment that doctors typically use ahead of surgery. According to the American Cancer Society (ACS), this treatment helps shrink cancerous tumors to make them easier to remove. Neoadjuvant chemotherapy may also kill cancerous tissue that is not yet visible on imaging tests.
Doctors often use neoadjuvant cnemotherapy as a measure to see how cancer might respond to a particular medication. If the cancer does not respond to that drug, doctors will use other drugs for treatment. They might decide to try another family of drugs or a combination oftwo or three different drugs.
Adjuvant cnemotherapy occurs after the primary treatment, rather than before. Oncologists may recommend either neoadjuvant or adjuvant cnemotherapy depending on various factors, including:
• cancer type;
• cancer progression;
• treatment goals, such as easing symptoms or slowing growth;
• the likelihood that a person will be able to tolerate multiple treatments.
According to an article published in 2015 by Daniel F. Hayes and Anne F. Schott in JNCI Monographs, neoadjuvant chemotherapy has no proven benefits other than:
• making the surgical removal of tumors easier;
• making inoperable tumors operable;
• reducing the need for mastectomies.
The authors note thatalthough neoadjuvant chemotherapy has other potential benefits, clinical trials have not conclusively proven them. Also, they state, it does not seem that this treatment directly increases survival rates in comparison with adjuvant therapy.
However, certain types of cancers respond especially well to neoadjuvant chemotherapy, and the treatment is sometimes so effective that it reduces the chance of cancer coming back.
(Lindsey Todd, www.medicalnewstoday.com, 15.07.2021. Adaptado)
Em relação ao quinto parágrafo, o termo inicial do sexto parágrafo However introduz a ideia de
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consequência.
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condição.
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concordância.